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Coronary artery thrombosis

Table of contents
Pathological anatomy and physiology Clinical presentation Workup Treatment

Thrombosis of the coronary arteries is a pathological condition in which blood clots form inside the coronary arteries.

Pathological anatomy and physiology

Thrombus formation can occur against the background of coronary artery atherosclerosis, lesions of the vascular endothelium; thromboembolism is also possible. The presence of a thrombus leads to coronary artery narrowing and subsequent ischemic damage to the myocardium.

Clinical presentation

Coronary artery thrombosis clinically manifests itself as stable / unstable angina pectoris, myocardial infarction or sudden cardiac death.

Workup

  • ECG: signs of ischemia;
  • EchoCG: areas of myocardial hypo / akinesis;
  • Angiography: visualization of the damaged area, assessment of the thrombus, determination of the circulatory disorders degree.

Treatment

Treatment is aimed at restoring effective blood flow to the coronary artery. Drug therapy involves use of antiplatelet agents and anticoagulants. Interventional techniques include thrombus aspiration and coronary artery stenting. Surgical treatment - myocardial revascularization.